Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Feb 22, 2017
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC02258  
Type Targeted MutationCartagena   wks
Species Mus musculus  
Strain name B6;129S(Cg)-Grin2c<tm1Nak>  
Former Common name NR2C KO  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo).  
Strain description NR2C (Grin2c) gene knockout mice. Homozygous mutant mice are viable and fertile.  
Colony maintenance Homozygote x Homozygote [or Crossing to C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Grin2c  
Symbol name glutamate receptor, ionotropic, NMDA2C (epsilon 3)  
Chromosome 11  
Common name GluRepsilon3, NMDAR2C, NR2C  
Symbol description No Data  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 11  
Common name neo; neomycin;  
Symbol description No Data  
References J Neurosci. 1996 Dec 15;16(24):7859-67.  
Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Neurosci., 16, 7859-7867 (1996).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 Genetic Background  
 2 Genotyping protocol <PCR>  
Depositor Sasaoka, Toshikuni (Niigata university)  Sasaoka, Toshikuni 
Strain Status /
Availability
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