Strain Information | |
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Image | |
BRC No. | RBRC09444 |
Type | Chemically-induced Mutation |
Species | Mus musculus |
Strain name | B6(C3)-Tuba1a<Rgsc1736> |
Former Common name | M1001736 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | |
Strain description | The founder mouse of M1-1736 exhibited an increased spontaneous-locomotor activity in open field and home cage. The mutant carries missense mutation in the Tuba1a. The heterozygote exhibited inattention to novel object and, disorganized structure of cerebral neocortex. The attention deficit and hyperactivity were improved by methylphenidate injection. |
Colony maintenance | |
References | Behav. Brain Res., 227, 167-174 (2012). 22101068 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | |
Research application | Developmental Biology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Behav. Brain Res., 227, 167-174 (2012). The RECIPIENT of for-profit institution must contact the DEPOSITOR separately. The RECIPIENT of not for-profit institution must contact and discuss in good faith with the DEPOSITOR regarding inventorship, ownership, patent filing and licese fees and others, prior to filing a patent or make a contract with license fees with a third party for invention or products obtained from research results by using the BIOLOGICAL RESOURCES. |
Depositor | RIKEN GSC (RIKEN GSC) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |