Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
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RBRC No. RBRC00052  
Type Wild-derived Inbred and Spontaneous Mutation   4wks
Species Mus musculus molossinus  
Strain name SHL  
Former Common name hyperlipidemia  
H-2 Haplotype No Data  
Background strain KOR [Mus musculus molossinus]  
Appearance
 1 Appearance white belly agouti  
Genotype No Data  
Strain development Spontaneous mutation arose in KOR wild-derived mouse colony. The mutant mice were maintained by sibling mating.  
Strain description SHL, spontaneously hyperlipidemia mutant mice. Spontaneous mutation arose in KOR mouse colony derived from Japanese wild-mice (Mus musculus molossius). Homozygous mutant mice show increased circulating cholesterol level. Homozygous mutant mice are viable and fertile (before onset of xanthoma). Females of homozygote show lower reproductive performance.  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Apoe  
Symbol name apolipoprotein E  
Chromosome 7  
Common name Apoe  
Symbol description No Data  
References The Lipid, 13, 318-324 (2002).
J Atheroscler Thromb. 2001;8(3):71-9.
Mamm Genome. 1999 Apr;10(4):352-7.  

Research applications Hematological Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results.  
Additional information
 1 Mouse of the Month Jan 2006  
Depositor Matsushima, Yoshibumi (Saitama Cancer Center)  Matsushima, Yoshibumi 
Strain Status /
Availability
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