Strain Data Sheet

RBRC00097

Strain Information

Image
BRC No.RBRC00097
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameC3H-Ttf/t<0>+
Former Common nameC3H-Ttf/t<0>+
H-2 Haplotype
ES Cell line
Background strainC3H/HeN
Appearanceagouti
Strain developmentMaintained by National Institute of Genetics.
Strain descriptionT, Brachyury, semidominant, Chr 17. t, t-complex, recessive, Chr 17. T/T homozygous embryos die at 10 days of gestation due to failure to form a normal mesoderm. T/+ heterozygote have a shortened tail and abnormal sacral vertebrae. T/t mice are tailless. tf/tf homozygous mice show repeated waves of hair loss and regrowth. tf gene is linked to the T/t complex.
Colony maintenanceSibling Mating (T: Heterozygote xHeterozygote; t: Heterozygote x Heterozygote, tf: Heterozygote x Hetrozygote)
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
tt-complex17t<0>t, 0

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tbrachyury17Tbrachyury

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Itpr3inositol 1,4,5-triphosphate receptor 317Itpr3<tf>tufted

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorToshihiko Shiroishi (National Institute of Genetics)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data