Strain Data Sheet
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Data update: Jul 19, 2019
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RBRC No. RBRC00142  
Type Spontaneous Mutation Congenic   8wks,♂
Species Mus musculus  
Strain name B6.Cg-Kit<W-v>/Rbrc  
Former Common name C57BL/6-KitW-v/+  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance white with black eyes  
Genotype a/a B/B C/C W/W  
 2 Appearance gray with light belly, white spot, light tail an feet  
Genotype a/a B/B C/C W/+  
 3 Appearance black  
Genotype a/a B/B C/C +/+  
Strain development Spontaneous mutation arosed in C57BL.  
Strain description B6.Cg-Kit<W-v>. Viable dominant spotting. Spontaneous mutation arosed in C57BL. The Kit<W-v> mutation arose spontaneously in the C57BL strain. Heterozygote for Kit<W-v> are gray with light belly, white spot, light tail and feet. Homozygous mice are white with black eyes. The c-Kit cDNA from Kit<W-v>/Kit<W-v> mice showed an AC to T point mutation at nucleotide 2007 that resulted in the change from threonine to methionine at position 660.  
Colony maintenance Sibling Mating (Heterozygote x Wild-type or Heterozygote)  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Kit  
Symbol name kit oncogene  
Chromosome 5  
Common name No Data  
Symbol description No Data  
References Cancer Res. 1992 Apr 15;52(8):2304-9.
Mech Dev. 2001 Oct;108(1-2):213-6.  
Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv).
Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv).
Research applications Cancer Research,
Dermatology Research,
Developmental Biology Research,
Endocrine Deficiency Research,
Immunology and Inflammation Research,
Mouse Models for Human Disease,
Neurobiology Research,
Reproductive Biology Research,
Sensorineural Research  
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)  
Additional information
 1 No Data  
Depositor Kitamura, Yukihiko (Osaka University)  Kitamura, Yukihiko 
Strain Status /
Availability
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