Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC00407  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129P2-Tcrd<tm1Mom>/ItoRbrc  
Former Common name TCR delta-KO, TCRd KO  
H-2 Haplotype No Data  
ES cell line E14 [129P2/OlaHsd]  
Donor strain 129P2/OlaHsd via E14 ES cell line  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance black  
Genotype a/a B/B C/C  
Strain development Developed by Drs. S. Itohara, P. Mombaerts and S Tonegawa, Howard Hughes Medical Institute, Massachusetts Institute of Technology in 1993.  
Strain description Developed by Drs. S. Itohara, P. Mombaerts and S Tonegawa, Howard Hughes Medical Institute, Massachusetts Institute of Technology in 1993.  
Colony maintenance Sibling Mating
Homozygous mutant mice are viable and fertile.  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Tcrd  
Symbol name T-cell receptor delta chain  
Chromosome 14  
Common name Tcr delta, Tcrdelta  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 14  
Common name neo; neomycin;  
Symbol description No Data  
References Cell. 1993 Feb 12;72(3):337-48.  
T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes.
Research applications Cell Biology Research,
Immunology and Inflammation Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Itohara et al., Cell, 72, 337-348 (1993).  
Additional information
 1 Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Itohara, ShigeYoshi (RIKEN Center for Brain Science)  Itohara, ShigeYoshi 
Strain Status /
Availability
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