Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC00688  
Type Targeted MutationCartagena   6wks,♂
Species Mus musculus  
Strain name B6;129S-Psap<tm2Suz>/JumaRbrc  
Former Common name mouse saposin A mutant mouse  
H-2 Haplotype No Data  
Donor strain 129/SvEv  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance black  
Genotype No Data  
 2 Appearance brown  
Genotype No Data  
Strain development 2001, Junko Matsuda, M.D. and Kunihiko Suzuki, M.D.
Neuroscience Center, Departments of neurology and Psychiatry, University of North Carolina, Chapel Hill, NC 27599-7250, U.S.A.  
Strain description Neurobiology Research, Metabolic Defects, Lysosomal Disease, Demyelinating disease  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Psap  
Symbol name prosaposin  
Chromosome 10  
Common name SGP-1, saposin A  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 10  
Common name No Data  
Symbol description No Data  
References Hum Mol Genet. 2001 May 15;10(11):1191-9.
Hum Mol Genet. 2001 Nov 1;10(23):2709-15.  
A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse.
A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse.
Research applications Cre/loxP system,
Metabolism Research,
Mouse Models for Human Disease,
Neurobiology Research  
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Matsuda, Junko (The University of Tokushima)  Matsuda, Junko 
Strain Status /
Availability
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