Strain Data Sheet
RBRC00872
Strain Information | |
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| Image | |
| BRC No. | RBRC00872 |
| Type | Chromosomal Aberration |
| Species | Mus musculus |
| Strain name | STOCK XO Eda<Ta>/O/Rbrc |
| Former Common name | XO |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | agouti with tabby [X<Ta>/X<Ta>, X<Ta>/Y] agouti with mosaic striped coat [X<Ta>/X] |
| Strain development | Deposited by Dr. Nobuo Takagi, Hokkaido University. |
| Strain description | Strain with monosomic X choromosomal aberration (X/O). This strain also has tabby (Eda<Ta>) mutation that affects both the coat color and hair pattern growth. The mice having X<Ta>/O or X<Ta>/Y show yellow coat, no hair on ears and tail, bald patch behind ears, and no guard hairs. Meanwhile, X<Ta>/X females show agouti with mosaic striped due to X-inactivation.agouti with tabby (yellow coat, no hair on ears and tail, bald patch behind ears, no guard hairs) (X<Ta>/X<Ta>, X<Ta>/Y); agouti with mosaic striped coat (X<Ta>/X) |
| Colony maintenance | This strain is maintained using tabby as a phenotypic marker to keep monosomic X chromosome condition. When wild-type female (X/O) is bred to hemizygote tabby male (X<Ta>/Y) in the first generation, hemizygote tabby female (X<Ta>/O) is bred to wild-type male (X/Y) in the second generation. On the contrary, when hemizygote tabby female (X<Ta>/O) is bred to wild-type male (X/Y) in the first generation, wild-type female (X/O) is bred to hemizygote male (X<Ta>/Y) in the second generation. |
| References | |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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| Donor DNA | |
| Research application | |
| Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
| Depositor | Nobuo Takagi (Hokkaido University) |
| Strain Status |  Frozen embryos |
| Strain Availability | Live mouse (3 to 6 months) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Miura K, Murata C, Harikae K, Suzuki H, Kanai-Azuma M, Kurohmaru M, Tsunekawa N, Kanai Y. Defects in the first wave of folliculogenesis in mouse XO ovaries. J Reprod Dev 63(3) 333-338(2017) 28392504 |