Strain Data Sheet

RBRC00948

Strain Information

Image
BRC No.RBRC00948
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameC.KOR1-Traf3ip2<adjm>
Former Common nameatopic dermatitis; BALB/c.NAD
H-2 Haplotype
ES Cell line
Background strainBALB/cAJcl
Appearancealbino
Strain developmentDeveloped by Dr. Yoshibumi Matsushima, Research Institute for Clinical Oncology, Saitama Cancer Center.
Strain descriptionBALB/c congenic strain having a sponatenous mutation found in a colony of the KOR inbred strain derived from Japanese wild mice. Homozygous mutant mice show high levels of serum IgE and an atopic dermatitis (AD)-like skin disease. The pehotype of this strain is less than on the KOR orinigal strain. Homozygous mutant mice are viable and fertile.
Colony maintenance
ReferencesJ. Immunol., 185, 2340-2349 (2010). 20660351

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Traf3ip2TRAF3 interacting protein 210Traf3ip2<adjm>atopic dermatitis from Japanese mice

Ordering Information

Donor DNA
Research applicationDermatology Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorYoshibumi Matsushima (Saitama Cancer Center)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data