Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC00993  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129S4-Sh2b3<tm1Rmp>/Rbrc  
Former Common name C57BL/6 Lnk -/-  
H-2 Haplotype No Data  
ES cell line AK7 [129S4/SvJaeSor]  
Donor strain 129S4/SvJaeSor via AK7 ES cell line  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Sh2b3  
Symbol name SH2B adapot protein 3  
Chromosome 5  
Common name Lnk; linker of T-cell receptor pathways  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 5  
Common name neo; neomycin;  
Symbol description No Data  
References Immunity. 2000 Nov;13(5):599-609.
Nat Genet. 2001 Mar;27(3):293-8.  
Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins.
Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Immunity 13, 599-609 (2000).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The depositor should be a co-author in the articles when the users publish their data using these mice for 1 year after provided.
Users should contact the depositor in the case of application for any patents with the results from these mice.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Takagi, Satoshi (National Center for Global Health and Medicine)  Takagi, Satoshi 
Strain Status /
Availability
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