Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
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  Mouse Marking
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RBRC No. RBRC01089  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129S-Nras<tm1Mok>  
Former Common name N-ras KO, B6-Nras KO  
H-2 Haplotype No Data  
Background strain C57BL/6  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo).  
Strain description Nras gene knockout mice. Homozygous mutant mice show no obvious abnormality.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Nras  
Symbol name neuroblastoma ras oncogene  
Chromosome 3  
Common name N-ras  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 3  
Common name neo; neomycin;  
Symbol description No Data  
References Oncogene. 1997 Sep 4;15(10):1151-9.
  
K-ras is essential for the development of the mouse embryo.
K-ras is essential for the development of the mouse embryo.
Research applications Cancer Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
EMBO J., 21, 1021-1030 (2002).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Sasaoka, Toshikuni (Niigata university)  Sasaoka, Toshikuni 
Strain Status /
Availability
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