Strain Information | |
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Image | |
BRC No. | RBRC01089 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129S-Nras<tm1Mok> |
Former Common name | N-ras KO, B6-Nras KO |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | C57BL/6 |
Appearance | |
Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo). |
Strain description | Nras gene knockout mice. Homozygous mutant mice show no obvious abnormality. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Oncogene, 15, 1151-1159 (1997). 9294608 EMBO J. 21(5):1021-30 (2002). 11867530 Oncogene, 27, 2961-2968 (2008). 18059342 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)3neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E coli neo, mouse N-ras genomic DNA, mouse Csde1 genomic DNA |
Research application | Cancer Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J., 21, 1021-1030 (2002). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Toshikuni Sasaoka (Niigata University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Genotyping protocol -PCR- Necessary documents for ordering: |
BRC mice in Publications |
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No Data |