Strain Information | |
---|---|
Image | |
BRC No. | RBRC01190 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | 129-Bcl11a<tm1Ngc>/Rbrc |
Former Common name | Evi9/BclIIa Knockout mice |
H-2 Haplotype | |
ES Cell line | CJ7 [129/SvlmJ] |
Background strain | |
Appearance | white-bellied agouti [A<w>/A<w> B/B C/C] |
Strain development | Developed by Drs. Pentao Liu and Neal G Copeland at NIH in 1999. A PGK-neo cassette replaced was transfered into CJ7 ES cells to replace exon 1 of Bcl11a gene. |
Strain description | Developed by Drs. Pentao Liu and Neal G Copeland at NIH in 1999. A PGK-neo cassette replaced was transfered into CJ7 ES cells to replace exon 1 of Bcl11a gene. |
Colony maintenance | Sibling Mating (Heterozygote x Wild-type, Heterozygote)Homozygous mutant mice die within 3-4hrs after birth. |
References | Nat. Immunol., 4, 525-532 (2003). 12717432 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Bcl11aB-cell CLL/lymphoma 11A (zinc finger protein)11Bcl11a<tm1Ngc>targeted mutation 1, Neal G Copeland2810047E18Rik, 4930538E20Rik, COUP-TF interacting protein 1, CTIP1, Evi9, mKIAA1809, mouse myeloid leukemia gene Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (Bovine)11GH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SAadenovirus major late transcript splice acceptor (SA) sequence11SA Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)11 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
---|---|
Donor DNA | adenovirus major late transcript splice acceptor (SA) sequence, E. coli lacZ, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, bovine growth hormone poly A, mouse Bcl11a genomic DNA |
Research application | Fluorescent Proteins/lacZ System Immunology and Inflammation Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nature Immunol., 6, 525-532 (2003). |
Depositor | Takuro Nakamura (Japanese Foundation for Cancer Research) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Genotyping protocol -PCR- Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |