Strain Information | |
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Image | |
BRC No. | RBRC01271 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129S6-Grm1<tm1Nak>/NakRbrc |
Former Common name | mGliR1TL36, B6;129-Grm1<tm(D854T)>/mGluR1TL36 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6J |
Appearance | |
Strain development | Developed by Drs. Sato Masaaki and Shigetada Nakanishi, Kyoto University Faculty of Medicine in 2004. |
Strain description | Grm1 (glutamate receptor, metabotropic 1)(mGluR1) knock-in mice, in which aspartate at position 854 was replaced with threonibe (termed D854T). D854T mutant mice homozygous show no obvious behavioural abnormality. |
Colony maintenance | |
References | Eur. J. Neurosci., 20, 947-955 (2004). 15305863 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Grm1glutamate receptor, metabotropic 110Grm1<tm1(D854T)>targeted mutation 1, (D854T)Gprc1a, Grm1, mGluR1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP |
Ordering Information | |
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Donor DNA | mouse glutamate receptor, metabotropic 1 genomic DNA, phage P1 loxP |
Research application | Cell Biology Research Neurobiology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. European Journal of Neuroscience, 20, 947-955 (2004).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT is required to obtain prior written consent form DEPOSITOR on use of the BIOLOGICAL RESOURCE. |
Depositor | Shigetada Nakanishi (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |