Strain Data Sheet

RBRC01271

Strain Information

Image
BRC No.RBRC01271
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S6-Grm1<tm1Nak>/NakRbrc
Former Common namemGliR1TL36, B6;129-Grm1<tm(D854T)>/mGluR1TL36
H-2 Haplotype
ES Cell line
Background strainC57BL/6J
Appearance
Strain developmentDeveloped by Drs. Sato Masaaki and Shigetada Nakanishi, Kyoto University Faculty of Medicine in 2004.
Strain descriptionGrm1 (glutamate receptor, metabotropic 1)(mGluR1) knock-in mice, in which aspartate at position 854 was replaced with threonibe (termed D854T). D854T mutant mice homozygous show no obvious behavioural abnormality.
Colony maintenance
ReferencesEur. J. Neurosci., 20, 947-955 (2004). 15305863

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Grm1glutamate receptor, metabotropic 110Grm1<tm1(D854T)>targeted mutation 1, (D854T)Gprc1a, Grm1, mGluR1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP10loxP

Ordering Information

Donor DNAmouse glutamate receptor, metabotropic 1 genomic DNA, phage P1 loxP
Research applicationCell Biology Research
Neurobiology Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. European Journal of Neuroscience, 20, 947-955 (2004).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT is required to obtain prior written consent form DEPOSITOR on use of the BIOLOGICAL RESOURCE.
DepositorShigetada Nakanishi (Kyoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data