Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC01356  
Type TransgeneCartagena   wks
Species Mus musculus  
Strain name C57BL/6-Tg(grm6-lacZ)35Kyo  
Former Common name ZF35  
H-2 Haplotype No Data  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Shigetada Nakanishi, Kyoto University Faculty of Medicine. The transgene was injected into the pronuclei of B6D2F1 fertilized eggs. C57BL/6 semicongenic.  
Strain description mGluR6 (glutamate receptor, metabotropic 6) gene is suggested to be responsible for ON responses in both the rod and cone systems. The transgene is mGluR6 gene fused to the beta-galactosidase reporter gene. This strain is useful for investigating the promoter function of the cell-specific and developmentally regulated expression of mGluR6.  
Colony maintenance Carrier x Carrier [or Crossing to C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol gpt  
Symbol name guanine phosphoribosyltransferase  
Chromosome UN  
Common name No Data  
Symbol description No Data  
 2 Symbol trpS  
Symbol name No Data  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter mouse mGluR6 promoter  
 3 Symbol lacZ  
Symbol name beta-galactosidase (E. coli)  
Chromosome UN  
Common name No Data  
Symbol description E. coli beta galactosidase  
References J Neurosci. 1997 May 1;17(9):3014-23.  
The mGluR6 5' upstream transgene sequence directs a cell-specific and developmentally regulated expression in retinal rod and ON-type cone bipolar cells.
Research applications Neurobiology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Neurosci., 17, 3014-3023 (1997).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT is required to obtain a prior written consent from the DEPOSITOR on use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Nakanishi, Shigetada (Kyoto University)  Nakanishi, Shigetada 
Strain Status /
Availability
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