Strain Information | |
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Image | |
BRC No. | RBRC01358 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Grm2-IL2RA)2Kyo |
Former Common name | MG-I2 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Drs. Dai Watanabe and Shigetada Nakanishi, Kyoto University Faculty of Medicine in 1998. |
Strain description | This transgenic mouse strain expresses the human IL2RA gene under the control of mouse GluR promoter. The IL2RA mRNA was highly expressed in Golgi cells of the cerebellum, granule cells of the main and accessory olfactory bulbs, the pontine nuclei, and neuronal cells of the cerebellum cortex. Homozygous and hemizygous mutant mice are viable and fertile. |
Colony maintenance | Homozygous and hemizygous mutant mice are viable and fertile. |
References | Cell, 95, 17-27 (1998). 9778244 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IL2RAInterleukin-2 receptor α-subunit (human)UNIL2RAmouse mGluR2 promoter |
Ordering Information | |
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Donor DNA | mouse mGluR2 promoter, human IL-2R alpha cDNA, polyA |
Research application | Neurobiology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 95, 17-27 (1998).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Shigetada Nakanishi (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |