Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC01479  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129S4-Cbfb<tm1Tno>/SataRbrc  
Former Common name PEBP1beta/CBFbeta KO  
H-2 Haplotype No Data  
Donor strain 129S4/SvJae via J1 ES cell line  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Cbfb  
Symbol name core binding factor beta  
Chromosome 8  
Common name PEA2, Pebp2, PEBP2b, Pebpb2  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 8  
Common name neo; neomycin;  
Symbol description No Data  
References Proc Natl Acad Sci U S A 1997 May 27;94(11):5697-702.  
Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc. Natl. Acad. Sci., 94 5697-5702 (1997).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT agrees to include the DEPOSITOR as a co-author in any publications resulted by the use of the BIOLOGICAL RESOURCE during the first 2 years after deposition by the DEPOSITOR to the RIKEN BRC.
The RECIPIENT should contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Satake, Masanobu (Institute of Development, Aging and Cancer, Tohoku University)  Satake, Masanobu 
Strain Status /
Availability
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