Strain Data Sheet
Data update: Aug 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC01658  
Type TransgeneCartagena   wks
Species Mus musculus  
Strain name C57BL/6J-Tg(CAG-hBACE1)2/Rbrc  
Former Common name C57BL/6J-TgN(b-actin-hBACE1)riken 2  
H-2 Haplotype No Data  
Background strain C57BL/6JJcl  
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report
Gene Details
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)  
 1 Symbol BACE1  
Symbol name beta-site APP cleaving enzyme 1 (human)  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References J Biol Chem 2005 Mar 4;280(9):8589-95. Epub 2004 Sep 13.  
In vivo cleavage of alpha2,6-sialyltransferase by Alzheimer beta-secretase.
Research applications Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Biol. Chem., 280, 8589-8595 (2005).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
I want users to include Dr. Yasuhiro Hashimoto and Dr. Kazuhiro Nakagawa as co-authors, when the future study using the transgenic mouse is published.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Hashimoto, Yasuhiro (RIKEN)  Hashimoto, Yasuhiro 
Strain Status /
(Expected delivery)

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