Strain Information | |
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Image | |
BRC No. | RBRC01659 |
Type | Transgene |
Species | Mus musculus |
Strain name | C.FVB-Tg(Itgax-DTR/EGFP)57Lan/Rbrc |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | BALB/cAnNCrlCrlj |
Appearance | |
Strain development | Developed by Steffen Jung in 2002. DTR/GFP under the control of the mouse Itgax promoer. The DTR/GFP1 fusion gene under the mouse Itgax promoter was injected into the pronuclei of FVB/N fertilized eggs. |
Strain description | This transgenic mice has a diphtheria toxin recepotr (DTR) and GFP fusion gene under under the control of the mouse Itgax promoer. The dendritic cells of this strain were transiently disrupted with DT inducible system. |
Colony maintenance | |
References | Immunity, 17, 211-220 (2002). 12196292 |
Health Report | |
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Examination Date / Room / Rack | 2024/02/26Room:4-BRack:I |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GFPGreen Fluorescent Protein (Aequorea victoria)UN Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBEGFheparin-binding EGF-like growth factor (human)UNHBEGFmouse Itgax promoter |
Ordering Information | |
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Donor DNA | mouse Itgax promoter, monkey heparin-binding EGF-like growth factor(hbEGF), jellyfish Green Fluorescence Protein (GFP) cDNA |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Research Purpose only. The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEVELOPER (Dr. Dan Littman). |
Depositor | Shigeo Koyasu (Keio University) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (3 to 6 months) |
Additional Info. | Genotyping protocol -PCR- Necessary documents for ordering:
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BRC mice in Publications |
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No Data |