Strain Data Sheet
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC01669  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.Cg-Hrh1<tm1(5MT)>/Rbrc  
Former Common name 5MT-H1R Knock-in mice  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Donor strain (C57BL/6 x CBA)F1 via TT2 ES cell line  
Background strain No Data  
 1 Appearance black  
Genotype a/a B/B C/C  
Strain development Developed by Shyuhei Horio and Hiroyuki Fukui, Tokushima University, and Takeshi Yagi, National Institute for Physiological Sciences in 2004. TT2 ES cells were used to generate the mutant mice. The mutant mice were crossed to C57BL/6 (semicongenic).  
Strain description H1R mutant gene knock-in mice. Details unknown.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJmsSlc]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Hrh1  
Symbol name histamine receptor H 1  
Chromosome 6  
Common name Bphs  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 6  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 3 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 6  
Common name neo; neomycin;  
Symbol description No Data  

Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
FEBS Lett., 573,226-230(2004). J. Pharmacol. Sci., 94, 410-419(2004).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT of BIOLOGICAL RESOURCE must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
The RECIPIENT agree to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE within two years after the deposition, the RECIPIENT must contact the DEPOSITOR about co-authorship.  
Additional information
 1 No Data  
Depositor Fukui, hiroyuki (The University Of Tokushima)  Fukui, hiroyuki 
Strain Status /
(Expected delivery)

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