Strain Data Sheet

RBRC01669

Strain Information

Image
BRC No.RBRC01669
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Hrh1<tm1(5MT)>/Rbrc
Former Common name5MT-H1R Knock-in mice
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Shyuhei Horio and Hiroyuki Fukui, Tokushima University, and Takeshi Yagi, National Institute for Physiological Sciences in 2004. TT2 ES cells were used to generate the mutant mice. The mutant mice were crossed to C57BL/6 (semicongenic).
Strain descriptionH1R mutant gene knock-in mice. Details unknown.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJmsSlc]
ReferencesJ Pharmacol Sci., 94, 410-419 (2004). 15107581
FEBS Lett., 573, 226-230 (2004). 15328002

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Hrh1histamine receptor H 16Hrh1<tm1Wtn>targeted mutation 1, Takeshi WatanabeBphs

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP6loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP6loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)6neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

Donor DNAphage P1 loxP sites, mouse phosphoglycerate kinase promoter (PKG promoter), E. coli neomycin resistance gene, rabbit beta-globin polyA, mutated murine histamin receptor H1 (Hrh1) cDNA, mouse Hrh1 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. FEBS Lett., 573,226-230(2004). J. Pharmacol. Sci., 94, 410-419(2004).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT of BIOLOGICAL RESOURCE must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
The RECIPIENT agree to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE within two years after the deposition, the RECIPIENT must contact the DEPOSITOR about co-authorship.
DepositorHiroyuki Fukui (Tokushima University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data