Strain Information | |
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Image | |
BRC No. | RBRC01669 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Hrh1<tm1(5MT)>/Rbrc |
Former Common name | 5MT-H1R Knock-in mice |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Shyuhei Horio and Hiroyuki Fukui, Tokushima University, and Takeshi Yagi, National Institute for Physiological Sciences in 2004. TT2 ES cells were used to generate the mutant mice. The mutant mice were crossed to C57BL/6 (semicongenic). |
Strain description | H1R mutant gene knock-in mice. Details unknown. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJmsSlc] |
References | FEBS Lett., 573, 226-230 (2004). 15328002 J Pharmacol Sci., 94, 410-419 (2004). 15107581 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PKG promoter), E. coli neomycin resistance gene, rabbit beta-globin polyA, mutated murine histamin receptor H1 (Hrh1) cDNA, mouse Hrh1 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. FEBS Lett., 573,226-230(2004). J. Pharmacol. Sci., 94, 410-419(2004).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT of BIOLOGICAL RESOURCE must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. The RECIPIENT agree to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE within two years after the deposition, the RECIPIENT must contact the DEPOSITOR about co-authorship. |
Depositor | Hiroyuki Fukui (Tokushima University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |