Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC01708  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6.Cg-Tg(Mt1-RET)242Ina  
Former Common name 242 RET  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Masashi Kato, Nagoya University Graduate School of Medicine. The Mt1-RET transgene was injected into the fertilized eggs of (BALB/c x C57BL/6) x BALB/c mice. C57BL/6 and BALB/c mixed background.  
Strain description Mt1-Ret 242 transgenic mice. The mice express the human RET under the control of the mouse MT1 promoter/enhancer. Mt1-RET homozygous mutant mice are embryonic lethal.  
Colony maintenance Carrier x Noncarrier  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Tg(Mt1-RET)242Ina  
Symbol name transgene insertion 242, Izumi Nakashima  
Chromosome UN  
Common name Tg(Mt1-RFP/FET)242Num  
Symbol description No Data  
 2 Symbol No Data  
Symbol name SV40 splicing signal-polyadenylation site  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter mouse metallothionein 1 promoter/enhancer  
 3 Symbol RET  
Symbol name recombinant RET proto-oncogene (human)  
Chromosome UN  
Common name RET51, RET9  
Symbol description No Data  
References EMBO J. 1991 Nov;10(11):3167-75.  
Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene.
Research applications Cancer Research,
Dermatology Research,
Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.  
Additional information
 1 Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Kato, Masashi (Chubu University College of Life and Health Sciences)  Kato, Masashi 
Strain Status /
Availability
(Expected delivery)

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