Strain Information | |
---|---|
Image | |
BRC No. | RBRC01841 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Tg(CAG-G0S2)3Noj/NojRbrc |
Former Common name | AILE1 TG (ATG3), B6.Cg-Tg(hGOS2)3Noj |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Norikazu Yabuta and Hiroshi Nojima, Research Institute for Microbial Diseases, Osaka University in 2004. The transgene was injected into the pronuclei of B6D2F1 fertilized eggs. C57BL/6 and DBA/2 mixed (B6 semicongenic). |
Strain description | These transgenic mice express human GOS2 (AILE1) gene that was a gene identified as systemic lupus erythematosus (SLE)-upregutated gene by microarray screening. |
Colony maintenance | Carrier x Noncarrier [C57BL/6NCrSlc] |
References | DNA Res., 12, 429-439 (2005). 16769699 DNA Res., 15, 253-265 (2008). 18562305 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter AILE1augmented expression in SLEUNAILE1CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) |
Ordering Information | |
---|---|
Donor DNA | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), human Aile1 cDNA |
Research application | Mouse Models for Human Disease |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. DNA Res., 12, 429-439 (2005).The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. |
Depositor | Hiroshi Nojima (Osaka University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |