Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC01890  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name C.Cg-Clec10a<tm1Tats>/TatsRbrc  
Former Common name mMgl1 lacZ knock in mice (BALB/c)  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain BALB/cAnNCrlCrlj  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kaori Denda and Tasturo Irimura, Graduate School of Pharmaceutical Sciences, The University of Tokyo. TT2 ES cells derived from B6CBAF1 were used to generate the knockout mice. RBRC01889: backcrossed to C57BL/6J. RBRC01890: BALB/c semicongenic (BALB/c, C57BL/6 and BALB/c mixed).  
Strain description Mgl1 gene knockout mice. Exons 2 to 10 were replaced with a PGK-neo and lacZ cassette. The MGL is one of the calcium-dependent (C type) lectins, which are intrinsic carbohydrate recognition proteins. C57BL/6 background (RBRC01889) and BALB/c mixed background (RBRC01890). Under investigation (details unknown).  
Colony maintenance Heterozygote x Wild-type [BALB/cAnNCrlCrlj]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Clec10a  
Symbol name macrophage galactose N-acetyl-galactosamine specific lectin 1  
Chromosome 11  
Common name Mgl1  
Symbol description No Data  
 2 Symbol GH  
Symbol name Growth hormone polyA (Bovine)  
Chromosome 11  
Common name No Data  
Symbol description No Data  
 3 Symbol lacZ  
Symbol name beta-galactosidase (E. coli)  
Chromosome 11  
Common name No Data  
Symbol description E. coli beta galactosidase  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 11  
Common name neo; neomycin;  
Symbol description No Data  
References No Data  
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.  
Additional information
 1 Lab HP  
Depositor Irimura, Tatsuro (The University of Tokyo)  Irimura, Tatsuro 
Strain Status /
Availability
(Expected delivery)

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