Strain Data Sheet
RBRC01900
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC01900 |
| Type | Targeted Mutation and Transgene |
| Species | Mus musculus |
| Strain name | Tg(TCRaTCRb) Rag2<tm1Fwa> |
| Former Common name | BOG8 |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Eur. J. Immunol., 26, 2081-2086 (1996). 8814250 International Immunology, 8, 297-306 (1996). 8671615 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |
|---|---|
| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)2neo; neomycin; Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter TCRAV8J48C1Tcra cDNA from BOG8 T cell hybridomaUNTCRAV8J48C1MMLV Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter TCRBV8.2DJ1.1C2Tcrb gene from BOG8 T cell hybridomaUNTCRBV8.2DJ1.1C2Tcrb |
Ordering Information | |
|---|---|
| Donor DNA | α 鎖遺伝子(MMLV エンハンサー＆プロモーターを上流に持った V, J, C 領域を含む cDNA 2.1 kb) と β 鎖遺伝子(VDJ, C 領域を含むゲノムDNA 14.5 kb) の両者が導入されている。加えて RAG2 KO マウスとの交配により RAG2 遺伝子が欠損している。 RAG2 KO マウスは、RAG2 coding region が 1.1 kb PMC1neo/poly(A)+により置換されている。 |
| Research application | Immunology and Inflammation Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. International Immunology, 8, 297-306 (1996).1. Material is considered the proprietary property of Mitsubishi Kagaku Institute of Life Sciences (MITILS) and Mitsubishi Chemical Corporation (MCC). 2. Recipient Investigator agrees not to use Material for profit making or commercial purposes. 3. Recipient Investigator shall acknowledge the source of Material in any publication containing experimental results obtained with the use of Material. 4. At the conclusion of the research for which Material was requested, Recipient shall dispose of unused Material in an appropriate legal manner. 5. After providing Material, RIKEN BRC shall inform MCC of followings; names of Recipient and Recipient Investigator, purpose and date. |
| Depositor | Hajime Takayama (Mitsubishi Kasei Institute of Life Sciences) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
|---|
| No Data |