Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC01957  
Type Targeted Mutation CongenicCartagena  
Species Mus musculus  
Strain name B6.Cg-Blm<tm2Jtak>  
Former Common name Blmtm2Tak  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Blm  
Symbol name Bloom syndrome homolog (human)  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 2 Symbol tTA  
Symbol name tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)  
Chromosome No Data  
Common name E. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain  
Symbol description No Data  
 3 Symbol IRES  
Symbol name internal ribosomal entry site (EMCV)  
Chromosome No Data  
Common name internal ribosomal entry site from EMCV  
Symbol description No Data  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome No Data  
Common name neo; neomycin;  
Symbol description No Data  
 5 Symbol Nox4  
Symbol name NADPH oxidase 4 (human)  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
 6 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
 7 Symbol tetO  
Symbol name tetracycline operator (E. coli)  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
References Gene. 2006 Mar 15;369:80-9. Epub 2006 Jan 4.  
Bloom's syndrome gene-deficient phenotype in mouse primary cells induced by a modified tetracycline-controlled trans-silencer.
Research applications Cre/loxP system,
Tet system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University.  
Additional information
 1 Takeda Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Takeda, Junji (Osaka University)  Takeda, Junji 
Strain Status /
Availability
(Expected delivery)

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