Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC02106  
Type Targeted MutationCartagena   wks
Species Mus musculus  
Strain name B6.129-Lefty1<tm1Hmd>  
Former Common name lefty 1 null KO  
H-2 Haplotype No Data  
ES cell line E14 [129P2/OlaHsd]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Lefty1  
Symbol name left right determination factor 1  
Chromosome 1  
Common name Leftb, lefty-1, Stra3  
Symbol description No Data  
Promoter SV40 and herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 1  
Common name neo; neomycin;  
Symbol description No Data  
References Cell. 1998 Aug 7;94(3):287-97.  
lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal.
Research applications Developmental Biology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT must inform the DEPOSITOR the research project using the BIOLOGICAL RESOURCE.  
Additional information
 1 Mouse of the Month May 2007  
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology)  Hamada, Hiroshi 
Strain Status /
Availability
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