Strain Information | |
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Image | |
BRC No. | RBRC02140 |
Type | Transgene Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Tg(DBH-tauGFP)17 |
Former Common name | DBH-tauGFP17 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Kazuto Kobayashi, Fukushima Medical University School of Medicine in 1998. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The Tg mice were backcrossed to C57BL/6J over 20 times. Line 17 (RBRC02140), line 36 (RBRC02141). |
Strain description | These transgenic mice express a fusion gene of bovine tau protein and GFP under the control of the human DBH promoter in typical noradrenergic and adrenergic cell groups. Line 17 and 36 were generated. The expression level of Tg in each line was following order: 17 > 36 (developer’s information). |
Colony maintenance | |
References | Neurogastroenterol. Motil., 22(3):331-e86 (2010). 19775251 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GFPGreen Fluorescent Protein (Aequorea victoria)UNhuman dopamine beta hydroxylase (DBH) promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter taubovine tau protein cDNAUNtauhuman dopamine beta hydroxylase (DBH) promoter |
Ordering Information | |
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Donor DNA | human dopamine beta-hydroxylase(DBH) promoter, rabbit beta-globin intron, bovine tau protein cDNA, jellyfish green fluorescent protein (GFP) cDNA, rabbit beta- globin poly A, SV40 early gene poly A |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neurogastroenterol. Motil. 22(3):331-e86. PMID: 19775251 |
Depositor | Kazuto Kobayashi (Fukushima Medical University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |