Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC02293  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129P2-p130Cas<tm1.1Homy>  
Former Common name Cas-ex2<flox/flox>  
H-2 Haplotype No Data  
ES cell line E14 [129P2/OlaHsd]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2003.  
Strain description No Data  
Colony maintenance backcross to C57BL/6N (Heterozygote x C57BL/6NCrlCrlj)  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Bcar1  
Symbol name breast cancer anti-estrogen resistance 1  
Chromosome 8  
Common name Cas, Crkas, p130 Cas  
Symbol description No Data  
 2 Symbol Frt  
Symbol name yeast FRT (flippase recombination target) site  
Chromosome 8  
Common name No Data  
Symbol description No Data  
 3 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 8  
Common name No Data  
Symbol description No Data  
 4 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 8  
Common name No Data  
Symbol description No Data  
References Genes Cells. 2008 Feb;13(2):145-57.  
Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice.
Research applications Cell Biology Research,
Cre/loxP system,
FLP/frt system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Honda, Hiroaki (Tokyo Women's Medical University)  Honda, Hiroaki 
Strain Status /
Availability
(Expected delivery)

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