Strain Information | |
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Image | |
BRC No. | RBRC02293 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129P2-p130Cas<tm1.1Homy> |
Former Common name | Cas-ex2<flox/flox> |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Developed by Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2003. |
Strain description | |
Colony maintenance | backcross to C57BL/6N (Heterozygote x C57BL/6NCrlCrlj) |
References | Hepatology, 52(3), 1089-1099 (2010). 20623582 Genes Cells., 13(2):145-57 (2008). 18233957 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Bcar1breast cancer anti-estrogen resistance 18Bcar1<tm1.1Homy>targeted mutation 1.1, HomyCas, Crkas, p130 Cas Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site8Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP8loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP8loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, yeast (Saccharomyces cerevisiae) FRT site, mouse Cas genomic DNA |
Research application | Cell Biology Research Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Hiroaki Honda (Tokyo Women's Medical University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |