Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
Figure
  Order
RBRC No. RBRC02337  
Type Targeted MutationCartagena   wks
Species Mus musculus  
Strain name B6.129P2-Top2a<tm1Skmz>  
Former Common name Topoisomerase II aloha knockout mouse  
H-2 Haplotype No Data  
Background strain C57BL/6  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Top2a  
Symbol name topoisomerase (DNA) II alpha  
Chromosome 11  
Common name DNA Topoisomerase II alpha, Top-2  
Symbol description No Data  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 11  
Common name neo; neomycin;  
Symbol description No Data  
References Genes Cells. 2003 Apr;8(4):393-402.
  
Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha.
Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha.
Research applications Cancer Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genes Cells, 8, 393-402 (2003). Cancer Lett., 166, 71-77 (2001)
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Sekimizu, Kazuhisa (The University of Tokyo)  Sekimizu, Kazuhisa 
Strain Status /
Availability
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