Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
Figure
  Order
RBRC No. RBRC02342  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name C57BL/6-Gak<tm1Noj>/+  
Former Common name GAK+/-, Cyclin G-associated kinase(GAK) heterozygous mouse  
H-2 Haplotype No Data  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Norikazu Yabuta and Hiroshi Nojima, Research Institute for Microbial Diseases, Osaka University in 2007.  
Strain description Gak, cyclin G associated kinase gene knockout mice. Exons 2-4 of Gak gene were replaced with a pgk-neo cassette. Homozygous mutant mice die shortly after birth.  
Colony maintenance Heterozygote x Wild-type [or Crossing to C57BL/6JJcl]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Gak  
Symbol name cyclin G associated kinase  
Chromosome 5  
Common name D130045N16Rik, MGC:31204, GAK-kd  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 5  
Common name neo; neomycin;  
Symbol description No Data  
References   
Research applications Cancer Research,
Cell Biology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Tabara H et al., "Neonatal lethality in knockout mice expressing the kinase-dead form of the gefitinib target GAK is caused by pulmonary dysfunction." PLoS One 2011;6(10):e26034
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.  
Additional information
 1 No Data  
Depositor Nojima, Hiroshi (Osaka university)  Nojima, Hiroshi 
Strain Status /
Availability
(Expected delivery)

back Back
RIKEN BioResource Research Center

English page click here ANIMAL SEARCH SYSTEM