Strain Data Sheet
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Data update: Aug 20, 2019
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RBRC No. RBRC02427  
Type Targeted Mutation and TransgeneCartagena  
Species Mus musculus  
Strain name B6.Cg-Kras<tm1Mok> Tg(hKrasPAC)1Mok  
Former Common name K-ras KO, K-ras(PAC)Tg, B6-Kras KO/KrasPAC Tg  
H-2 Haplotype No Data  
ES cell line CCE/EK.CCE [129S/SvEv-Gpi1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences.  
Strain description Double mutant mice having a Kras gene knockout and human KRAS gene transgene.  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Kras  
Symbol name v-Ki-ras2 Kirsten rat sacroma viral oncogene homolog  
Chromosome 6  
Common name K-ras, Ki-ras, Kras-2, Kras2  
Symbol description No Data  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 6  
Common name neo; neomycin;  
Symbol description No Data  
 3 Symbol KRAS  
Symbol name v-Ki-ras2 Kirsten rat sacroma viral oncogene homolog (human)  
Chromosome UN  
Common name K-ras, Ki-ras, Kras-2, Kras2  
Symbol description No Data  
References Oncogene. 1997 Sep 4;15(10):1151-9.  
K-ras is essential for the development of the mouse embryo.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Oncogene, 15, 1151-1159 (1997).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
Depositor Sasaoka, Toshikuni (Niigata university)  Sasaoka, Toshikuni 
Strain Status /
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