Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
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RBRC No. RBRC02457  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6;129S-Drd2<tm1Mok> Drd3<tm1Mok>  
Former Common name D2RD3R-KO  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences.  
Strain description D2R (Drd2) and D3R (Drd3) genes double knockout mice. Mixed background.  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Drd3  
Symbol name dopamine receptor 3  
Chromosome 16  
Common name D3 receptor, D3R  
Symbol description No Data  
 2 Symbol Drd2  
Symbol name dopamine receptor 2  
Chromosome 9  
Common name D2 receptor, D2R, Drd-2  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 3 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 16  
Common name neo; neomycin;  
Symbol description No Data  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 9  
Common name neo; neomycin;  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 5 Symbol Ecogpt  
Symbol name E.coli xanthine phosphoribosyltransferase  
Chromosome 16  
Common name No Data  
Symbol description No Data  
References Genes Cells. 1996 Feb;1(2):253-68.  
Dopamine D2 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitary.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genes Cells, 1, 253-268 (1996).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
Depositor Sasaoka, Toshikuni (Niigata university)  Sasaoka, Toshikuni 
Strain Status /
Availability
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