Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
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RBRC No. RBRC02468  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6;129S-Irf3<tm1Ttg>/Mok  
Former Common name IRF3-KO  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo).  
Strain description IRF3 gene knockout mice.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol No Data  
Symbol name No Data  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
References Immunity. 2000 Oct;13(4):539-48.  
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Immunity, 13, 539-548 (2000).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
Depositor Sasaoka, Toshikuni (Niigata university)  Sasaoka, Toshikuni 
Strain Status /
Availability
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