Strain Data Sheet

RBRC02468

Strain Information

Image
BRC No.RBRC02468
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S-Bcl2l12/Irf3<tm1Ttg>/MokRbrc
Former Common nameIRF3-KO, B6;129S-Irf3<tm1Ttg>/Mok
H-2 Haplotype
ES Cell lineCCE/EK.CCE [129S/SvEv-Gpi1<c>]
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo).
Strain descriptionIRF3 gene knockout mice.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesImmunity. 2000 13(4):539-48. 11070172

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Irf3interferon regulatory factor 37Irf3<tm1Ttg>targeted mutation 1, Tadatsugu TaniguchiC920001K05Rik, IRF-3

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Bcl2l12BCL2-like 12 (proline rich)7Bcl2l12<tm1Ttg>targeted mutation 1, Tadatsugu TaniguchiBcl2-L12, Bcl-L12

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse IRF-3 genomic DNA, mouse Bcl2l12 genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Immunity, 13, 539-548 (2000). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data