Strain Data Sheet

RBRC02478

Strain Information

Image
BRC No.RBRC02478
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Grin2a<tm1Nak> Drd2<tm1Mok> Drd3<tm1Mok> Drd4<tm1Mok>
Former Common nameB6-NR2A/D2R/D3R/D4R KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionNR2A (Grin2a), D2R (Drd2), D3R (Drd3) and D4R (Drd4) genes multiple knockout mice.
Colony maintenance
ReferencesGenes Cells. 1(2):253-68 (1996). 9140068
J. Neurosci., 16, 7859-7867 (1996). 8987814

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Drd3dopamine receptor 316Drd3<tm1Mok>targeted mutation 1, Motoya KatsukiD3 receptor, D3R

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)16Grin2a<tm1Nak>targeted mutation 1, Shigetada Nakanishi

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
EcogptE.coli xanthine phosphoribosyltransferase16Ecogptmouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)16neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)16neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Drd4dopamine receptor 47Drd4<tm1Mok>targeted mutation 1, Motoya KatsukiD4R, Drd-4

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
EcogptE.coli xanthine phosphoribosyltransferase7Ecogptmouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7neo; neomycin;mouse RNA polymerase II large subunit promoter

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Drd2dopamine receptor D29Drd2<tm1Mok>targeted mutation 1, Motoya KatsukiD2 receptor, D2R, Drd-2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)9neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse NMDAR2A genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli xanthine phosphoribosyltransferase (Ecogpt), mouse Dopamine receptor2 genomic DNA, mouse Dopamine receptor3 genomic DNA, mouse Dopamine receptor4 genomic DNA
Research applicationNeurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 16, 7859-7867 (1996). Genes Cells, 1, 253-268 (1996).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data