Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
Figure
  Order
RBRC No. RBRC02573  
Type Targeted MutationCartagena   wks
Species Mus musculus  
Strain name B6.129-Traf5<tm1Hna>  
Former Common name B6.traf5<-/->, TRAF5 KO,C57BL/6  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance black  
Genotype a/a B/B C/C  
Strain development Developed by Drs. Hiroshi Nakano and Haruhio Koseki in 1999.  
Strain description Homozygous mutant mice show defects in lymphocyte activation.  
Colony maintenance Sibling Mating (Homozygote x Homozygote)
Homozygous mutant mice are viable and fertile.  
Health Report
BRC facility Health Report in the last year and a half

Examination Date Room Rack
May 10, 2010 2-検 E
Mar 8, 2010 2-検 E
Jan 12, 2010 2-検 E
Nov 9, 2009 2-検 E
Sep 7, 2009 2-検 E
Jul 6, 2009 2-検 E
May 12, 2009 2-検 E
May 11, 2009 2-検 E
Gene Details
Promoter No Data  
 1 Symbol Traf5  
Symbol name Tnf receptor-associated factor 5  
Chromosome 1  
Common name No Data  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 1  
Common name neo; neomycin;  
Symbol description No Data  
References J Immunol. 2004 Apr 1;172(7):4292-7.

  
TNF receptor-associated factor 5 limits the induction of Th2 immune responses.
TNF receptor-associated factor 5 limits the induction of Th2 immune responses.
TNF receptor-associated factor 5 limits the induction of Th2 immune responses.
Research applications Immunology and Inflammation Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The recipient of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Nakano, Hiroyasu (Juntendo University)  Nakano, Hiroyasu 
Strain Status /
Availability
(Expected delivery)

back Back
RIKEN BioResource Research Center

English page click here ANIMAL SEARCH SYSTEM