Strain Data Sheet
Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC02575  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.Cg-Trp53<tm1Sia>/SiaRbrc  
Former Common name p53(-) (Acc. No. CDB0001K)  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Trp53  
Symbol name transformation related protein 53  
Chromosome 11  
Common name p53  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 11  
Common name neo; neomycin;  
Symbol description No Data  
References Oncogene. 1993 Dec;8(12):3313-22.  
Enhanced proliferative potential in culture of cells from p53-deficient mice.
Research applications Cancer Research,
Cell Biology Research,
Immunology and Inflammation Research,
Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0001K and the BIOLOGICAL RESOURCE is requested ( (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested, Oncogene. 1993 Dec; 8 (12): 3313-22. (3) In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested, "We acknowledge Dr. AIZAWA in CDB for providing us the p53 mutant mice (Acc. No. CDB0001K)." (4) Please inform the DEVELOPER ( about the paper when published.  
Additional information
 1 No Data  
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology)  RIKEN, CDB 
Strain Status /
(Expected delivery)

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