Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC02687  
Type Targeted Mutation CongenicCartagena  
Species Mus musculus  
Strain name B6.Cg-Tnc<tm1Sia> Tnxb<tm1Kmat>  
Former Common name Tnx-/-(A1),Tnc-/- double deficient, TNX-/-(A1),TNC-/-  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Tnxb  
Symbol name tenascin XB  
Chromosome 17  
Common name Tnx  
Symbol description No Data  
 2 Symbol Tnc  
Symbol name tenascin C  
Chromosome 4  
Common name C130033P17Rik, Hxb, Ten, tenascin-C, TN, TN-C  
Symbol description No Data  
 3 Symbol lacZ  
Symbol name beta-galactosidase (E. coli)  
Chromosome 4  
Common name No Data  
Symbol description E. coli beta galactosidase  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 17  
Common name neo; neomycin;  
Symbol description No Data  
References Genes Cells 2001 Dec;6(12):1101-11.
Genes Cells 2004 Aug;9(8):737-48.
Genes Dev. 1992 Oct;6(10):1821-31.
J Invest Dermatol. 1998 Dec;111(6):930-5.
  
Tumour invasion and metastasis are promoted in mice deficient in tenascin-X.
Tumour invasion and metastasis are promoted in mice deficient in tenascin-X.
Tumour invasion and metastasis are promoted in mice deficient in tenascin-X.
Tumour invasion and metastasis are promoted in mice deficient in tenascin-X.
Tumour invasion and metastasis are promoted in mice deficient in tenascin-X.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Jpn J. Cancer Res., 73, 968-975 (2002).
The RECIPIENT must contact the DEPOSITOR in the case of application for any publications, patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Matsumoto, Kenichi (Shimane University)  
Strain Status /
Availability
(Expected delivery)

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