Strain Data Sheet
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC02692  
Type Targeted MutationCartagena   wks
Species Mus musculus  
Strain name B6.129X1-Lilrb4a<tm1Ttk>  
Former Common name gp49B  
H-2 Haplotype No Data  
ES cell line RW4 [129X1/SvJ]  
Background strain C57BL/6NCrlCrlj  
 1 Appearance black  
Genotype a/a B/B C/C  
Strain development Developed by Dr. Toshiyuki Takai, Tohoku University in 2008.  
Strain description Lilrb4 knock-out mice. Lilrb4 (gp49B) is a member of the immunoglobulin superfamily, containing immunoreceptor tyrosine-based inhibitory motifs that can deliver an inhibitor signal in mast and NK cells.  
Colony maintenance Sibling x Sibling (Homozygote x Homozygote)
Homozygous mice are viable and fertile.  
Health Report
BRC facility Health Report in the last year and a half

Examination Date Room Rack
Jul 10, 2017 2-検 G
May 15, 2017 2-検 G
Mar 13, 2017 2-検 G
Jan 16, 2017 2-検 G
Nov 14, 2016 2-検 G
Sep 12, 2016 2-検 G
Jul 11, 2016 2-検 G
May 16, 2016 2-検 G
Gene Details
Promoter No Data  
 1 Symbol Lilrb4a  
Symbol name leukocyte immunoglobulin-like receport, subfamily B, member 4  
Chromosome 10  
Common name CD85K, Gp49b, HM18, ILT3, Lilrb4  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 10  
Common name neo; neomycin;  
Symbol description No Data  

Research applications Immunology and Inflammation Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Biol. Chem., 273, 1070-1074 (1998). J. Immunol., 165, 4970-4977 (2000).  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Takai, Toshiyuki (Tohoku University)  Takai, Toshiyuki 
Strain Status /
(Expected delivery)

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