Strain Information | |
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Image | |
BRC No. | RBRC02712 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Gpr126<tm1Taki> |
Former Common name | DREG Knock-out Mouse |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | C57BL/6 |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Dr. Akiyama T, The University of Tokyo. |
Strain description | Gpr129 knock-out mice. Gpr129, G-protein-coupled receptor 126 is a member of seven-transmembrane proteins related to family-B G-protein- coupled receptors (LNB-TM7), expresses at high levels in the heart and somites during mouse embryogenesis and in the adult lung. Homozygous mutant mice are embryonic lethal (E12.5). |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Genes Cells, 9, 549-560 (2004) 15189448 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gpr126G protein-coupled receptor 12610Gpr126<tm1Taki>targeted mutation 1, Tetsu Akiyama1190004A11Rik, DREG, LOC215798 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)10 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)10neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | E. coli neo, E. coli lacZ, polyoma enhancer/herpes simplex virus thymidine kinase promoter (HSV tk promoter)(MC1), Phage P1 loxP sites |
Research application | Developmental Biology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells, 9, 549-560 (2004).The DEPOSITOR should be a co-author in articles when the RECIPIENTs publish their data using the BIOLOGICAL RESOURCE for two years after deposition to the RIKEN BRC. After two years from deposition, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Tetsu Akiyama (The University of Tokyo) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |