Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Aug 20, 2019
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RBRC No. RBRC02771  
Type TransgeneCartagena  
Species Mus musculus  
Strain name C.B-17/Icr Prkdc<scid>-Tg(INS-TRECK/DTR)1Rin  
Former Common name BALB/c Prkdc-Tg(INS-TRECK/DTR)1Rin  
H-2 Haplotype No Data  
Background strain C.B-17/Icr-scid/Jcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kunie Matsuoka and Hiromichi Yonekawa, Tokyo Metropolitan Institute of Medical Science. The transgene was injected into the pronuclei of C.B-17/Icr-scid fertilized eggs. RBRC02767 (line 5), RBRC02768 (line 14), RBRC02769 (line 17), RBRC02770 (line 33), RBRC02771 ((scid background, the same line as the #70 in BBRC2013 article).  
Strain description scid-INS-TRECK Transgenic mice, having the diphtheria toxin receptor (hDTR) driven by the human insulin promoter and Prkdc<scid> mutation. Hyperglycemia was observed within 3 days after the administration of DT.  
Health Report
BRC facility Health Report in the last year and a half

Examination Date Room Rack
Mar 7, 2016 2-検 F
Nov 9, 2015 2-検 G
Sep 7, 2015 2-検 G
Jul 6, 2015 2-検 G
May 11, 2015 2-検 G
Mar 9, 2015 2-検 G
Jan 13, 2015 2-検 G
Nov 10, 2014 2-検 G
Gene Details
Promoter No Data  
 1 Symbol Prkdc  
Symbol name protein kinase, DNA activated, catalytic polypeptide  
Chromosome 16  
Common name No Data  
Symbol description No Data  
Promoter human Insulin promoter  
 2 Symbol HBEGF  
Symbol name heparin-binding EGF-like growth factor (human)  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References
  

Research applications Diabetes and Obesity Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. Biophys. Res. Commun., 436, 400-405 (2013).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. The RECIPIENT of BIOLOGICAL RESOURCE, who belongs to a profit organization must obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 Organization HP  
 2 Genotyping protocol <PCR>  
Depositor Yonekawa, Hiromichi (Tokyo Metropolitan Institute of Medical Science)  Yonekawa, Hiromichi 
Strain Status /
Availability
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