Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC02831  
Type Targeted MutationCartagena   wks
Species Mus musculus  
Strain name B6.129S6-Gcg<tm1Yhys>  
Former Common name No Data  
H-2 Haplotype No Data  
Background strain C57BL/6JJmsSlc  
Appearance
 1 Appearance black  
Genotype a/a B/B C/C  
Strain development Developed by Dr. Yoshitaka Hayashi, Nagoya University in 2007. Gcg gene was disrupted by introduction of GFP cDNA. GFP expresses in Gcg positive cells.  
Strain description Glucagon, Gcg deficient mice. Homozygous mutant mice lack peptides derived from proglucagon.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJmsSlc]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Gcg  
Symbol name glucagon  
Chromosome 2  
Common name No Data  
Symbol description No Data  
 2 Symbol GFP  
Symbol name Green Fluorescent Protein (Jellyfish)  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 3 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome No Data  
Common name neo; neomycin;  
Symbol description No Data  
References   
Research applications Fluorescent Proteins/lacZ System  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC's MTA. Please also read Schedule B.  
 2 Mouse of the Month Nov 2012  
 3 Genotyping protocol <PCR>  
Depositor Hayashi, Yoshitaka (Nagoya University)  Hayashi, Yoshitaka 
Strain Status /
Availability
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