Strain Data Sheet
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC02846  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name 129S6/SvEvTac-Crx<tm1Clc>  
Former Common name CRX K.O.  
H-2 Haplotype No Data  
Background strain 129S6/SvEvTac  
 1 Appearance light-bellied agouti  
Genotype A/A B/B C/C  
Strain development Developed by Dr. Takahisa Furukawa, Harvard Medical School in 1999.  
Strain description Crx gene knockout mice. Homozygous mutant mice lack a outer segment of retinal photoreceptor.  
Colony maintenance Sibling x Sibling (Homozygote x Homozygote)
Homozygous mutant mice are viable and fertile  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Crx  
Symbol name cone-rod homeobox containig gene  
Chromosome 7  
Common name cone-rod homeobox containg gene  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome No Data  
Common name neo; neomycin;  
Symbol description No Data  
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Nat. Genet., 23, 466-470 (1999).  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Furukawa, Takahisa (Osaka Bioscience Institute)  Furukawa, Takahisa 
Strain Status /
(Expected delivery)

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