Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC03326  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129-Ttll6<tm1Seto>/SetoRbrc  
Former Common name TL6 KO  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Koji Ikegami and Mitsutoshi Setou, Mitsubishi Kagaku Institute of Life Sciences. 129 derived ES cells were used. The mice were crossed to C57BL/6J.  
Strain description Ttll6 (TL6) gene knockout mice. Exons 2 to 4 were replaced with a neo cassette. A region including an initiation site of TTL domain was removed. Initiation codon is in exon 1. Homozygous mutant mice show no obvious abnormality. Expression pattern : Not examined.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Ttll6  
Symbol name tubulin tyrosine ligase-like family, member 6  
Chromosome 11  
Common name No Data  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 11  
Common name neo; neomycin;  
Symbol description No Data  
References No Data  
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences)  Setou, Mitsutoshi 
Strain Status /
Availability
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