Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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  Mouse Marking
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  Order
RBRC No. RBRC03423  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name ApoE4/CRE KO  
Former Common name No Data  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description No Data  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Apoe  
Symbol name apolipoprotein E  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 2 Symbol APOE4  
Symbol name apolipoprotein E4 (human)  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 3 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 7  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 7  
Common name neo; neomycin;  
Symbol description No Data  
References Hum Mol Genet. 2000 Feb 12;9(3):353-61.  
Altered cholesterol metabolism in human apolipoprotein E4 knock-in mice.
Research applications Cre/loxP system,
Hematological Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.  
Additional information
 1 No Data  
Depositor Fujita, Shinobu (Mitsubishi Kagaku Institute of Life Sciences)  Fujita, Shinobu 
Strain Status /
Availability
(Expected delivery)

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