Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC03656  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6;129-Arx<tm(GCG)Kki>/7-2Rbrc  
Former Common name Arx (GCG)7-2KI (B6)  
H-2 Haplotype No Data  
ES cell line CCE/EK.CCE [129S/SvEv-Gpi1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kunio Kitamura, Mitsubishi Kagaku Institute of Life Sciences. CCE/EK.CCE ES cells were used to generate the mutant mice.  
Strain description Arx GCG 7 repeats knock-in mice. 7 repeats of the GCG triple were inserted at the codon 330 of Arx gene. C57BL/6 mixed background (RBRC03654 and RBRC03656), 129 background (RBRC03655), C3H mixed background (RBRC03657), ICR mixed background (RBRC03665).  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Arx  
Symbol name aristaless related homeobox  
Chromosome X  
Common name No Data  
Symbol description No Data  
 2 Symbol No Data  
Symbol name SV40 polyA signal  
Chromosome X  
Common name No Data  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 3 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome X  
Common name No Data  
Symbol description No Data  
References   
Research applications Mouse Models for Human Disease,
Neurobiology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.  
Additional information
 1 No Data  
Depositor Kitamura, Kunio (Mitsubishi Chemical Corporation)  Kitamura, Kunio 
Strain Status /
Availability
(Expected delivery)

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