Strain Information | |
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Image | |
BRC No. | RBRC04287 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | Pcdhg-DgHS1-5 |
Former Common name | DgHS1-5 |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Takeshi Yagi, Graduate School of Frontier Biosciences, Osaka University in 2009. TT2 ES cells were used. |
Strain description | Pcdhg knockout mice. The gHS1-5 genomic region of the Pcdhg gene was deleted. Diap1 gene was also deleted. About 30% homozygous mutant mice die within 3 days after birth. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6J(Crlj)] |
References | J Biol Chem. , 286, 31885-31895 (2011). 21771796 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IRESinternal ribosomal entry site (EMCV)18 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)18 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter taubovine tau protein cDNA18tau |
Ordering Information | |
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Donor DNA | Mouse Pcdh-g gene, P1 phage loxP, E. coli LacZ, Encephalomyocarditis virus ires (internal ribosone entry site), bovine tau |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System Neurobiology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. If the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR. |
Depositor | Takeshi Yagi (Osaka University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |