Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
Figure
  Order
RBRC No. RBRC04489  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.B6CB-Hoil1<tm1Kiwa>  
Former Common name HOIL-1L KO  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kazuhiro Iwai, Graduate School of Medicine, Osaka City University in 2004. TT2 ES cells were used to generate the mutant mice. The mice were backcrossed to C57BL/6.  
Strain description Rbck1 (HOIL-1L) knockout mice. Homozygous mutant mice show attenuated TNF-alpha mediated NF-kappaB activation.  
Colony maintenance Heterozygote x Homozygote [or Crossing to C57BL/6JJmsSlc]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Rbck1  
Symbol name RanBP-type and C3HC4-type zinc finger containing 1  
Chromosome 2  
Common name No Data  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 2  
Common name No Data  
Symbol description No Data  
References   
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Nat. Cell. Biol., 11, 123-132 (2009).
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Iwai, Kazuhiro (Kyoto University)  Iwai, Kazuhiro 
Strain Status /
Availability
(Expected delivery)

back Back
RIKEN BioResource Research Center

English page click here ANIMAL SEARCH SYSTEM